Check with your pharmacist. These people may lose weight as their anemia improves because theyre more active. Common side effects of Venofer include: muscle cramps, nausea, vomiting, stomach pain, strange taste in the mouth or decreased sense of taste, diarrhea, constipation, headache, cough, sore throat, sinus pain, congestion, back pain, joint pain, dizziness, weakness, tired feeling, anxiety, ear pain, swelling of the arms/legs, or Learn more about these, as well as the symptoms, diagnosis, and treatments. Iron infusions are given directly into a vein. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. This allows them to manage any side effects that you may have following your dose. Seriousside effectsshould be reported to a physician and/orPharmDfor medical advice. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. If your symptoms or health problems do not get better or if they become worse, call your doctor. These changes could help improve your anemia on a long-term basis. Heres some detail on certain side effects this drug may cause. Your doctor will monitor your hemoglobin level to tell if Injectafer is working for you. Potential injection site discoloration has happened. After 5 weeks of treatment: This study didnt determine if either drug was better than the other. Symptoms include shock, dangerously low blood pressure, loss of consciousness, and/or collapse. One study of just under 5000 HRT users found that 43% were affected. All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. Nose or throat irritation. Tell all of your health care providers that you take Venofer. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. Most people do not know how long theirside effectswill last until they go through them. Serious side effects from Injectafer arent common, but they can occur. We comply with the HONcode standard for trustworthy health information. Canada residents can call a provincial poison control center. Below are examples of these side effects. (A medication class is a group of medications that work in a similar way.). If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). Others last much longer (even a lifetime), which can be quite traumatizing to people. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. Copyright 1996-2023 Cerner Multum, Inc. Any long-term side effects/dangers from iron infusions? But so far I feel better than before the infusion. Which tests can diagnose iron deficiency anemia? If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. You may report side effects to FDA at 1-800-FDA-1088. The next time the doctor prescribesprescription medication, ask aboutcommonside effectsand if they are known to last a short or longtime. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. You can also write a reminder on your calendar. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. But its only approved for use in people with CKD who may or may not need dialysis. (A generic drug is an exact copy of the active drug in a brand-name medication.). Details. Learn about the causes, symptoms, diagnosis, and treatment of this. They can tell you about other medications that may work well for you. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. Joint pain. And these two doses need to be separated by at least 7 days. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. There may be drug take-back programs in your area. Best food forward: Are algae the future of sustainable nutrition? Find out what health conditions may be a health risk when taken with Venofer Vial However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. And this could lead to weight gain, if they increase their food intake. All of the people took iron by mouth for 2 weeks. The benefit of treating your condition during pregnancy may outweigh any risks. However, Injectafer has been studied for use in children with iron deficiency anemia (IDA). Also tell them about any vitamins, herbs, and supplements you use. This could happen because Injectafer helps increase their hemoglobin levels, but it doesnt address the underlying cause of their anemia. (See also Notes section.). The information provided is not intended to replace your healthcare provider's medical advice. Diarrhea. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. If you have questions about side effects, call your doctor. However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. Severeside effectsmay end up causing a lot of disruption in a persons life. However, since peoples bodies react so differently to drugs, they often have to change their stance on certain drugs. Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. Injectafer infusions are given over a period of at least 15 minutes. Weight changes may be due to symptoms of anemia improving. After receiving IV iron therapy, you will be monitored for 30 minutes to make sure you do not have an allergic reaction or a drop in blood pressure. "That's why it's so . Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. All rights reserved. And this over-activation is what may lead to an allergic reaction or a delayed allergic reaction. You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. Hemoglobin is a protein thats found in your RBCs. Together, you and your doctor can develop a treatment plan thats best for you. Do not share your drugs with others and do not take anyone else's drugs. There are currently no generic forms of either drug. No, you wont need to take iron pills while youre using Injectafer. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. Typical Injectafer doses for iron deficiency anemia (IDA) depends on your body weight. Possibleside effectsareweight gainand suicidal thoughts. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. As a result, you may not make as much EPO as usual. If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. For example: Say you weigh 105 pounds (about 48 kilograms). Change in taste. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. Throw away unused or expired drugs. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. This means you would get two Injectafer doses of 720 mg each. However, consuming large amounts of alcohol can actually cause anemia in some people. Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. If you have a severe allergic reaction to Injectafer after youve left the medical facility where you received your dose of the drug, call your doctor right away. If youre wondering how longside effectslast, youll be happy to know they can last just a few hours. Do not flush down a toilet or pour down a drain unless you are told to do so. I'm contemplating getting infusions again but I've always been a bit worried that they could cause issues in the long run. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. The following information describes dosages that are commonly used or recommended. Below are examples of these side effects. But its not known whether this poses any risk to a child whos breastfed. If you notice any changes to your normal blood pressure, call your doctor right away. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. What is Venofer? 2 0 obj This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your . If either is present, do not use the liquid. Injectafer isnt a medication that youll take regularly on a schedule. I can't take oral supplements because they cause horrible debilitating Constipation. In the first group, some people continued taking iron by mouth, while other people took Injectafer. Its responsible for carrying oxygen throughout your body. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. 1xo`[kg'#KS#.#`uv:PM1+Ob`>y/8:6Ghl:y9B+-,9m[ What to know about iron deficiency anemia, took oral iron treatment and didnt have improvement in their IDA or had side effects that couldnt be managed, or, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, have a medical condition that affects their bodys ability to absorb phosphorus, take medications that affect how well their, ferrous sulfate (Fer-Iron, Slow-FE, Feosol), people who took Injectafer had their hemoglobin level increase by an average of 1.1 grams per deciliter (g/dL), people who took Venofer had their hemoglobin increase by an average of 0.9 g/dL. Cardiovascular health: Insomnia linked to greater risk of heart attack. Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Does Venofer Vial interact with other medications? This is not a complete list of possible side effects. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. endobj If you notice other effects not listed above, contact your doctor or pharmacist. *Patients are calculated based on an estimated annual cumulative dose. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. This information should not be used to decide whether or not to take Venofer or any other medicine. Injectafer and Venofer have different approved uses, but theyre both used to treat IDA in people with CKD. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Orofer S 50 Injection 1 Injection in 1 Packet 147. Iron infusion side effects vary depending on which form is being used. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing Your doctor will do laboratory tests to monitor your response. For more information about taking Injectafer during pregnancy, see the section Injectafer and pregnancy above. Keep all regular medical and laboratory appointments. Back pain. Injectafer contains the active drug ferric carboxymaltose. Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. Together, they can recommend ways to help you manage a body weight thats healthy for you. People with IDA have low blood levels of hemoglobin. WebMD does not provide medical advice, diagnosis or treatment. 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If you have questions about drinking alcohol while youre taking Injectafer, talk with your doctor. 4 0 obj Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. Venofer may cause significant hypotension (decreased blood pressure). These lists contain examples of serious side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). Renal elimination is negligible. For some people, it may be OK to continue taking a multivitamin that contains iron. Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Theyll recommend how to manage your condition. Precautions. And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. There are 2 tests that your doctor will likely Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. (A medication class describes a group of drugs that work in the same way.). The oral form of the drug, called sucroferric oxyhydroxide and used . With anemia, you have a low level of red blood cells (RBCs) in your body. The signs and symptoms of anaphylaxis include dizziness or fainting, skin flushing and itchiness, difficulty breathing, rapid heart rate, low blood pressure and sudden anxiety. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. <> In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. For this purpose, Injectafer is approved for use in adults who either: Venofer is also approved to treat IDA. This survey is being conducted by the WebMD marketing sciences department. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. Side effects from HRT depend on a number of factors: Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. Here are answers to some frequently asked questions about Injectafer. If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. We cancelled my 5th because of the reaction. Can poor sleep impact your weight loss goals? I got Venofer twice in the last few years and now my iron deficiency is worse than ever, first time my hemoglobin is down to 11,2. In clinical studies, diarrhea was reported in less than 1% of people taking Injectafer. These pregnancy-related problems include preterm delivery and low birth weight of your infant. Here we look at how Injectafer and Feraheme are alike and different. (IV iron is absorbed by the body more rapidly than oral iron.) stream The use of Injectafer and Feraheme in treating IDA in these adults has been directly compared in a clinical study. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). Fortunately, knowing how longside effectslast can help those suffering know what to donext. Heart failure: Could a low sodium diet sometimes do more harm than good? Its caused by your body not having enough iron, which is needed to make hemoglobin. (A generic drug is an exact copy of the active drug in a brand-name medication.) Other drugs are available that can treat iron deficiency anemia (IDA). Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Injectafer helps to treat IDA by providing an iron infusion directly into your body. 3 0 obj With IDA, you have low hemoglobin levels. fever. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. The drug helps increase your hemoglobin level back to a value thats within the normal range. Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. But in some people, Injectafer can cause symptoms of hypophosphatemia to occur. * This is a partial list of mild side effects from Injectafer. dizziness. Theyll likely have you stop taking the pills while youre using Injectafer. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. Then the study was split into the following two groups, which are discussed below. Taking a larger dose of LSD can extend the duration of the trip, but generally, the main effects of LSD don't tend to last any longer than 12 hours. Yes, in some cases it may. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Instead, youll start by receiving just one treatment course of Injectafer. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. xmq92\Kz!yIP}2~(?c/JUCK2~o_N=>K$o/_7'Z+nRkKM^y{u|ZFh$v}]O~vfo=.GowGFodVj-[-~x]Kg~9H'%h={OX/#S|Mc~|]_2nv`wwotn/+$G[{hGrP}sbZG-RGf#l~~l|Qnccml_iPy]G\17c,yPF[28z&I'+B(?rrvi,G?}/;'?;pm>?.i42ONmk~ai_u0z9o_? If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. There are different types of anemia, but IDA is the most common type. If you have questions about side effects, call your doctor. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. Dilute Venofer in a maximum of 250 mL of 0.9% NaCl. Sharing this information can help you avoid potential interactions. Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. Details. Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking.
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